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Tests & Procedures
Endoscopic Sleeve Gastroplasty
Endoscopic sleeve gastroplasty is a less invasive weight-loss procedure that aims to reduce stomach volume using endoscopic suturing.
ESG reduces stomach capacity using full-thickness endoscopic suturing, typically without external incisions. The result is a narrower, sleeve-like stomach shape that can help patients feel full earlier and support reduced calorie intake. Compared with traditional bariatric surgery, ESG is generally considered less invasive, but it is still a medical procedure with risks, follow-up needs, and realistic limitations. [1][2][3][5]
This procedure is most often discussed for adults with obesity who have not achieved adequate results with structured diet, exercise, and medical management, or for those who may not be ideal candidates for bariatric surgery. It is not a cosmetic intervention and should not be viewed as an effortless alternative to long-term behavior change. Good candidates are typically those who understand the need for nutritional follow-up, gradual diet progression, and sustained lifestyle change after the procedure. [1][3][4][6]
Before ESG, evaluation generally includes medical review, assessment of obesity-related conditions, nutritional counseling, and exclusion of problems that may make the procedure inappropriate or unsafe. The care team may also assess eating patterns, reflux symptoms, medication use, and psychological readiness. This pre-procedure phase is important because the goal is not simply to shrink the stomach, but to create a realistic, durable treatment plan. [1][2][3]
The procedure is performed endoscopically, usually under anesthesia or deep sedation. Using a suturing device passed through the mouth, the endoscopist places stitches inside the stomach to reduce its internal volume. No external incisions are made. Patients often go home the same day or after a short observation period, depending on the center and individual case. [1][2][4]
Weight loss after ESG can be clinically meaningful, especially when combined with structured dietary counseling and physical-activity planning. Improvements may also be seen in obesity-related conditions such as type 2 diabetes, blood pressure, and quality of life in selected patients. However, outcomes vary. The procedure is a tool that supports weight management; it does not replace long-term engagement with treatment. [3][4][5][7]
Possible risks include abdominal pain, nausea, vomiting, reflux-related symptoms, dehydration, bleeding, and, more rarely, serious complications requiring further intervention. The overall safety profile is generally favorable in experienced hands, but patients should not interpret “less invasive” as “risk-free.” Informed consent should include discussion of expected benefits, likely follow-up, dietary changes, and the possibility that weight loss may be less than hoped if lifestyle support is not maintained. [1][2][3][5]
Nutrition after ESG is a central part of success. Patients are typically advanced gradually from liquids to soft foods and then to longer-term portion-controlled eating. Protein intake, hydration, meal structure, and avoidance of maladaptive eating patterns matter. A procedure that physically changes the stomach can still fail to meet expectations if the post-procedure care pathway is weak. [1][2][4]
In summary, ESG is a less invasive endoscopic option for selected adults with obesity and may support substantial weight loss when paired with comprehensive follow-up. It should be viewed not as a one-day solution, but as one component of long-term obesity care. [1][3][4][7]
References
- 1.Mayo Clinic. Endoscopic sleeve gastroplasty. 2023. https://www.mayoclinic.org/tests-procedures/endoscopic-sleeve-gastroplasty/about/pac-20393958
- 2.Cleveland Clinic. Endoscopic Sleeve Gastroplasty (ESG). 2025. https://my.clevelandclinic.org/health/treatments/24771-endoscopic-sleeve-gastroplasty
- 3.Abu Dayyeh BKA, et al. IFSO Bariatric Endoscopy Committee Evidence-Based Review and Position Statement on Endoscopic Sleeve Gastroplasty for Obesity Management. Obes Surg. 2024. PubMed: https://pubmed.ncbi.nlm.nih.gov/39482444/
- 4.Docimo S Jr, et al. Endoscopic sleeve gastroplasty and its role in the treatment of obesity: a systematic review. Surg Obes Relat Dis. 2023. PubMed: https://pubmed.ncbi.nlm.nih.gov/37813705/
- 5.Hedjoudje A, et al. Efficacy and Safety of Endoscopic Sleeve Gastroplasty: Systematic Review and Meta-Analysis. Clin Gastroenterol Hepatol. 2020. PubMed: https://pubmed.ncbi.nlm.nih.gov/31442601/
- 6.World Health Organization. Obesity and overweight. 2025. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
- 7.Espinet-Coll E, et al. Endoscopic sleeve gastroplasty (ESG) – A semi-systematic review of current evidence, metabolic impact, special populations, and comparative strategies. 2025. PubMed: https://pubmed.ncbi.nlm.nih.gov/41410254/
