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Diseases & Conditions
Cold Sore
Learn what causes cold sores, how they spread, typical symptoms and when treatment or medical review is needed.
A cold sore is a blistering infection around the lips or mouth caused by herpes simplex virus, most often HSV-1. Once acquired, the virus remains in the body and can reactivate later. [1][2]
What is Cold sore?
Many people first notice tingling, burning or tightness before a blister appears. The blister then breaks, crusts and heals over days. Recurrences may be triggered by sun exposure, stress, fever or illness. [1][3]
What are the symptoms and what causes it?
Typical symptoms are tingling, pain and grouped fluid-filled blisters around the lips. The infection spreads through close contact, especially when active lesions are present, though asymptomatic shedding can also occur. [1][2][3]
How is it diagnosed?
Diagnosis is often clinical based on the appearance and location. Testing is usually reserved for atypical cases, severe disease or people with weakened immune systems. [1][2]
What are the treatment options?
Treatment may include antiviral creams or oral antiviral medication, especially when started early. Supportive care, avoiding irritation and reducing transmission risk are also important. [1][2][4]
Possible complications and when to seek medical care
Most cold sores heal without serious problems, but eye symptoms, extensive lesions, severe pain or infection in an immunocompromised person needs medical care. [1][2][3]
What may help in daily life?
Avoid kissing, sharing lip products or close oral contact while sores are active. Sun protection on the lips may reduce recurrences in some people. [2][3]
Common mistakes during follow-up
A common mistake is touching lesions and then touching the eyes. Another is assuming every sore around the mouth is the same condition. [2][4]
FAQ
What is cold sore?
Cold sore is explained by its symptoms, causes, diagnosis and treatment plan. The most important step is matching the symptoms with the correct medical evaluation. [1][2]
When should I see a doctor for cold sore?
Seek medical review if symptoms are persistent, worsening, recurrent or clearly affecting daily life. Urgent review is needed when warning signs or severe symptoms are present. [1][2]
Can cold sore improve without treatment?
Some mild cases or symptom flares may settle, but not every condition should be watched at home. Improvement does not always mean the underlying problem has been resolved. [1][2]
How is cold sore diagnosed?
Diagnosis usually starts with a medical history and examination, then moves to targeted tests depending on the symptom pattern and suspected cause. [1][2]
Why does follow-up matter?
Follow-up helps confirm the diagnosis, assess response to treatment and detect complications or recurrence earlier. [1][2]
References
- 1.Mayo Clinic. *Cold sore - Symptoms and causes*. 2024. https://www.mayoclinic.org/diseases-conditions/cold-sore/symptoms-causes/syc-20371017
- 2.Mayo Clinic. *Cold sore - Diagnosis and treatment*. 2024. https://www.mayoclinic.org/diseases-conditions/cold-sore/diagnosis-treatment/drc-20371023
- 3.NHS. *Cold sores*. 2025. https://www.nhs.uk/conditions/cold-sores/
- 4.WHO. *Herpes simplex virus fact sheet*. 2025. https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus
